Wide dissemination of OXA-23-producing carbapenem-resistant Acinetobacter baumannii clonal complex 22 in multiple cities of China

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Wide dissemination of OXA-23-producing carbapenem-resistant Acinetobacter baumannii clonal complex 22 in multiple cities of China.

OBJECTIVES In this study, multilocus sequence typing (MLST) was used to describe the genetic backgrounds of carbapenem-resistant Acinetobacter baumannii (CRAB) and carbapenem-susceptible A. baumannii (CSAB) from multiple cities of China. METHODS One hundred and fifty-two CRAB and 74 CSAB isolates obtained from 16 cities of China were selected for molecular characterization by MLST. eBURST was...

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Carbapenem-resistant Acinetobacter baumannii producing OXA-23 in Thailand.

We investigated the resistance determinant of 13 clinical isolates of carbapenem-resistant Acinetobacter baumannii collected from a regional hospital in the north of Thailand. All isolates were multidrug resistant and produced the OXA-23 carbapenemase. The bla(OXA-23) gene was found adjacent to ISAba1. Furthermore, two isolates carried the metallo beta-lactamase gene, bla(IMP). The bla(OXA-23) ...

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Outbreak of carbapenem-resistant Acinetobacter baumannii producing the OXA-23 enzyme in Curitiba, Brazil.

Carbapenem-resistant Acinetobacter baumannii isolates were obtained from eight patients in two hospitals in Curitiba, Brazil. The isolates were multiresistant, belonged to a single strain, and produced the OXA-23 carbapenemase. Treatment options were limited, although the isolates were susceptible to polymyxin B in vitro. The strain contributed to the deaths of five patients.

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Identification of OXA-23-producing Acinetobacter baumannii

A Liakopoulos1, V Miriagou2, E A Katsifas3, A D Karagouni3, G L Daikos4, L S Tzouvelekis5, E Petinaki ([email protected])1 1. Department of Microbiology, University Hospital of Larissa, Larissa, Greece 2. Laboratory of Bacteriology, Hellenic Pasteur Institute, Athens, Greece 3. Faculty of Biology, Department of Botany, Microbiology Group, University of Athens, Athens, Greece 4. 1st Department...

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Outbreak of carbapenem-resistant Acinetobacter baumannii producing the carbapenemase OXA-23 in a tertiary care hospital of Papeete, French Polynesia.

Carbapenem-resistant Acinetobacter baumannii isolates were obtained from 24 patients between March and May 2004 at the Centre Hospitalier de Polynésie Française, Tahiti, French Polynesia. The isolates were multidrug resistant, produced the carbapenemase OXA-23, and belonged to a single clone presenting several subtypes, suggesting an endemic situation. This study further illustrates the global ...

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ژورنال

عنوان ژورنال: Journal of Antimicrobial Chemotherapy

سال: 2010

ISSN: 1460-2091,0305-7453

DOI: 10.1093/jac/dkq027